A Mini-Review on the Structural Characteristics and Anticancer Activity of Nagilactones-Reference-Cited by-全球学者库

A Mini-Review on the Structural Characteristics and Anticancer Activity of Nagilactones

Published:2024-10 Issue:5 Volume:10 Page:
ISSN:2215-0838
Container-title:Current Traditional Medicine
language:en
Short-container-title:CTM

Author:

Xiao Yuchen¹²³,Yong Jianping⁴,Lu Canzhong¹⁴³

Affiliation:

1. Fujian Institute of Research on the Structure of Matter, Haixi Institute, Chinese Academy of Sciences, Xiamen, China

2. Shanghai Tech University, Shanghai, China

3. University of Chinese Academy of Sciences, Beijing, China

4. Xiamen Institute of Rare-earth Materials, Haixi Institute, Chinese Academy of Sciences, Xiamen, China

Abstract

Abstract: Natural products provide abundant resources for the development of new drugs. Podocarpus nagi is an arbor of Podocarpus L'Hér. ex Persoon. Its fruits, leaves, and roots exhibit a broad spectrum of pharmacological activities (such as antitumor, plant growth regulation, termite killing, and insect larval toxicity), which have been used in Yao folk for a long history. Nagilactone is one of the key components discovered in Podocarpus nagi, which has a variety of structures and a broad spectrum of antitumor activities. In this mini-review, the structures and spectral characteristics, together with the antitumor activities and the structure-activity relationships of nagilactones, are summarized by searching the database in order to provide detailed references for researchers to elucidate and modify their structures.

Funder

National Natural Science Foundation of China

Science and Technology Planning Program of Xiamen

Publisher

Bentham Science Publishers Ltd.

Subject

Complementary and alternative medicine,Drug Discovery

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