An Update on the Anti-diabetic Functions of Genistein: A Soybean (Glycine max (L.) Merr.) Isoflavone-Reference-Cited by-同舟云学术

An Update on the Anti-diabetic Functions of Genistein: A Soybean (Glycine max (L.) Merr.) Isoflavone

Published:2024-04 Issue:2 Volume:10 Page:
ISSN:2215-0838
Container-title:Current Traditional Medicine
language:en
Short-container-title:CTM

Author:

Sharifinejad Niusha¹²,Hooshyar Matin³,Ramezankhah Mohammad⁴,Shamsehkohan Amirreza⁵,Saie Rezvan⁶,Sahebjam Mina⁵,Aleebrahim-Dehkordi Elahe⁷,Orandi Shirin⁸,Faraji Ali⁹,Deravi Niloofar³

Affiliation:

1. Student Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran

2. Alborz office of USERN, Universal Scientific Education and Research Network (USERN), Alborz University of Medical Sciences, Karaj, Iran

3. Student Research Committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4. Student Research Committee, School of Medicine, Babol University of Medical Sciences, Babol, Iran

5. Student Research Committee, Faculty of Nutrition and Food Science, Tabriz University of Medical Sciences, Tabriz, Iran

6. Student Research Committee, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran

7. Medical Plants Research, Center, Basic Health Sciences Institute, Shahrekord University of Medical Sciences, Shahrekord, Iran

8. Department of Clinical Biochemistry, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran

9. Department of Medicine, Islamic Azad University of Medical Sciences, Tehran, Iran

Abstract

Abstract: Type 2 diabetes mellitus (T2DM) is a developing worldwide issue. Traditionally, different plants have been used throughout history to lower blood glucose and improve the impact of diabetes. Also, today, many natural products have been introduced to lower blood glucose in T2DM patients. The beneficial effects of genistein, the most essential and abundant isoflavone of soybean (Glycine max (L.) Merr.), on blood glucose and other metabolic indicators, as well as diabetesrelated complications, have been widely investigated. In the current narrative review, through a thorough search from "2013-2020” in “PubMed", "Scopus", “ResearchGate”, “Google Scholar”, and "Web of Science" databases, we have retrieved, reviewed, and summarized all clinical trials, as well as in vitro and in vivo studies on the anti-diabetic potential of genistein.

Publisher

Bentham Science Publishers Ltd.

Subject

Complementary and alternative medicine,Drug Discovery

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