Bioactive Potential of Artocarpus heterophyllus Lam.: PRISMA Based Review

Author:

Singh Sonia1ORCID,Gupta Anushka1,Gupta Neha1

Affiliation:

1. Institute of Pharmaceutical Research, GLA University, 17 km Stone, NH-2, Mathura-Delhi Road Mathura, Chaumuhan, Uttar Pradesh 281406, India

Abstract

Introduction: In India, the plant Artocarpus heterophyllus Lam. is commonly known as "Jackfruit" and has been generally used as food and in many traditional medicines. Objective: The present manuscript aimed to collect description information on phytochemistry, ethnomedical uses, pharmacological activities, and patent of A. heterophyllus Lam. that may help in making a bridge between the research gaps as well as the upcoming future findings. Materials and Methods: The literature survey was based on a PRISMA systematic study that gathered information from various sources, including journals, e-books, and digital databases such as Scopus, Web of Science, Pubmed, and Science Direct from 1991 to 2021. Results: Several bioactive constituents are characterized, including flavonoids, chalcones, flavanols, terpenoids, stilbenoids, and xanthones in the fruit. It also contains tannins, quercetin, gallic acid, saponins, artocarpanone and artocarpin. Many pharmacological studies stated the therapeutic potential of Jackfruit, such as antioxidant, antimicrobial, anti-inflammatory, antifungal, anticancer, and antidiabetic properties. Conclusion: The present manuscript summarizes the phytochemistry and pharmacological properties of A.heterophyllus Lam. And it is also providing information in-vitro and in-vivo concerning experimental studies with patent data which, in turn, makes the herbal drug a promising source in the nutrition and therapeutic aspects.

Publisher

Bentham Science Publishers Ltd.

Subject

Complementary and alternative medicine,Drug Discovery

Reference109 articles.

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3. Hari A.; Revikumar K.G.; Divya D.; Artocarpus: A review of its phytochemistry and pharmacology. J Pharm Search 2014,9(1),7-12

4. Vazhacharickal P.J.; Sajeshkumar N.K.; Mathew J.J.; Chemistry and medicinal properties of jackfruit (Artocarpus heterophyllus): a review on current status of knowledge. In J Innov Res Rev 2015,3(2),83-95

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