Affiliation:
1. Guru Gobind Singh College of Pharmacy, Yamuna Nagar 135001, Haryana, India
Abstract
Background:
Polymers are the backbone of modern pharmaceutical formulations and
drug delivery technologies. Polymers that may be natural, synthetic, or semisynthetic are used to
control the release of drugs in a pre-programmed fashion. The drug delivery systems are mainly
prepared to enhance the bioavailability, site-specific release, sustained release, controlled release,
i.e., to modify the release of drug from dosage form may be a tablet, capsule, etc.
Objective:
The objective of the present study is to overview the recent patents concerning the application
of eudragit in the prevention of cancer and other ailments. Eudragit polymers are polymethacrylates
and may be anionic, cationic, or non-ionic polymers of methacrylic acid, dimethylaminoethyl
methacrylates, and methacrylic acid esters in varying ratios. Eudragit is available in
various grades with solubilities at different pH, thus helping the formulators design the preparation
to have a well-defined release pattern.
Method:
In this review, patent applications of eudragit in various drug delivery systems employed
to cure mainly cancer are covered.
Results :
Eudragit has proved its potential as a polymer to control the release of drugs as coating polymer
and formation of the matrix in various delivery systems. It can increase the bioavailability of
the drug by site-specific drug delivery and can reduce the side effects/toxicity associated with anticancer
drugs.
Conclusion:
The potential of eudragit to carry the drug may unclutter novel ways for therapeutic intercessions
in various tumors.
Publisher
Bentham Science Publishers Ltd.
Subject
Pharmacology (medical),Cancer Research,Drug Discovery,Oncology,General Medicine
Cited by
4 articles.
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