A Comprehensive Review of Systemic Targeted Therapies in Cancer Treatment

Author:

Lakkaniga Naga Rajiv1,Sharma Amit2,Jadhav Hemant R.2,Rai Anubhav1,Chandramoorthy Harish C.34,Kamli Hossam Mohammed5,Alshahrani Mohammad Y.5,Rajagopalan Prasanna5

Affiliation:

1. Department of Chemistry and Chemical Biology, Indian Institute of Technology (Indian School of Mines), Dhanbad, India

2. Laboratory of Pharmaceutical Chemistry, Department of Pharmacy, Birla Institute of Technology and Science, Pilani, India

3. Stem Cells & Regenerative Medicine Unit, College of Medicine, King Khalid University, Kingdom of Saudi Arabia

4. Department of Microbiology & Clinical Parasitology, College of Medicine, King Khalid University, Kingdom of Saudi Arabia

5. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Kingdom of Saudi Arabia

Abstract

Abstract: Cancer is one of the significant healthcare challenges in today’s world, even after advancements in modern science, including oncology. The complex nature of the disease, which involves multiple proteins and pathways, poses a substantial challenge in drug discovery. Several therapeutic options have emerged in the last decade. Systemic cancer therapies began with the advent of chemotherapy and were revolutionized with the development of targeted therapies. The present review is a definite overview of the advances in various therapeutic options for cancer, with a particular emphasis on targeted therapy using small molecules and biologicals.

Publisher

Bentham Science Publishers Ltd.

Subject

Cancer Research,Oncology,Molecular Medicine

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