Endophytic Fungi in the Fight Against Neglected Tropical Diseases

Author:

Costa Maria Beatriz Silva1,de Oliveira Camila Martins2

Affiliation:

1. Institute of Exact Sciences and Technologies, Federal University of Amazonas, Itacoatiara, Brazil

2. Institute of Exact and Natural Sciences, Federal University of Mato Grosso, Rondonópolis, Brazil

Abstract

Neglected tropical diseases are a serious global public health problem and they are one of the main causes of mortality and morbidity, especially in underdeveloped countries. These diseases have several implications for health and they are considered a priority in global eradication programs for disease control. The aim of this mini-review is to report recent studies on the fight against neglected diseases, namely dengue fever, chikungunya, zika, malaria protozoa, Chagas disease, leishmaniasis, schistosomiasis helminths, filariasis, and tuberculosis bacteria using extracts and isolated substances of endophytic fungi based on their bioactivity profiles in relation to these diseases.

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology,General Medicine

Reference76 articles.

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2. Rosário M.S.; de Oliveira M.L.; Lima C.A.; Vieira M.A.; Carneiro J.A.; Costa F.M.; Neglected tropical diseases: characteristics of the affected individuals and their spatial distribution Rev. Bras. Pesq. Saúde 2017,19(3),118-127

3. Scotti L.; Scotti M.T.; Perspectives in medicinal chemistry: Neglected diseases – new compounds and treatments. Curr Med Chem 2019,26(24),4501-4503

4. Mishra Y.; Singh A.; Batra A.; Sharma M.M.; Understanding the Biodiversity and Biological Applications of Endophytic Fungi: A Review. J Microb Biochem Technol 2014

5. Sudha V.; Govindaraj R.; Baskar K.; Al-Dhabi N.A.; Duraipandiyan V.; Biological properties of Endophytic Fungi. Braz Arch Biol Technol 2016,59

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