Advances on Monosaccharides and Oligosaccharides: Structural Modifications and Bioactivities

Author:

Li Shaochen1,Lv Min1,Zhang Shaoyong2,Xu Hui1

Affiliation:

1. College of Plant Protection, Northwest A&F University, Yangling 712100, Shaanxi Province, China

2. Key Laboratory of Vector Biology and Pathogen Control of Zhejiang Province, College of Life Science, Huzhou University, Huzhou 313000, Zhejiang Province, China

Abstract

Derivatives of monosaccharides and oligosaccharides play important roles in biological processes. Monosaccharides are the single carbohydrate building blocks, such as glucose, xylose, and fructose. Oligosaccharides are composed of 2-10 monosaccharides, including disaccharides and trisaccharides. Moreover, monosaccharides, oligosaccharides and their derivatives are vital molecules with various biological properties, including anticancer activity, antiviral activity, insecticidal activity, antimicrobial activity, and antioxidant activity. This review covers a survey of structural modifications, biological activities, and mechanisms of action of monosaccharides, oligosaccharides and their derivatives. Additionally, their structure-activity relationships are also concluded.

Funder

Special Funds of Central Colleges Basic Scientific Research Operating Expenses, Northwest A&F University

National Natural Science Foundation of China

Publisher

Bentham Science Publishers Ltd.

Subject

Drug Discovery,Pharmacology,General Medicine

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