Affiliation:
1. Glocal School of Pharmacy, Glocal University, Mirzapur Pole, Saharanpur, Uttar Pradesh, India
2. Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al‒Qura University, Makkah, 21955,
Saudi Arabia
Abstract
Abstract:
The pyridazinone derivatives have diverse biological potential and are easily synthesized.
Due to this, researchers and chemists have paid attention to the design and development of novel and
effective bioactive compounds. The substituted pyridazines have shown a wide range of pharmacological
activities, such as analgesic, anti-inflammatory, antibacterial, antifungal, anticonvulsant, antidepressant,
antianxiety, antitubercular, anti-malarial, anticancer, anti-HIV, platelet inhibitory, hypotensive,
cardiotonic, etc. In the current circumstances, it can be concluded that pyridazinone derivatives
have great prospects, which remain to be revealed.
Publisher
Bentham Science Publishers Ltd.
Reference180 articles.
1. Deker Barton F.R.S.; David Ollis F.R.S.; Chairman and deputy
chairman of the editorial board. Comprehensive organic chemistry. The Synthesis Reaction of the Organic Compound 1993,3,249
2. Tsubaki K.; Taniguchi K.; Tabuchi S.; Okitsu O.; Hattori K.; Seki J.; Sakane K.; Tanaka H.; A novel pyridazinone derivative as a nonprostanoid PGI2 agonist. Bioorg Med Chem Lett 2000,10(24),2787-2790
3. Wang T.; Dong Y.; Wang L.C.; Chen Z.; Synthesis and bioactivity of 6-phenyl-4,5-dihydro-3(2H)-pyridazinone derivatives. Arzneimittelforschung 2007,57(10),641-646
4. Asif M.; Alam M.; Study of heterocyclic-fused pyridazinone analogues having phosphodiestrase-IV inhibitor activities as anti-inflammatory agents. J Med Chem Sci 2020,3(2),109-117
5. Abdelbaset M.S.; Abdel-Aziz M.; Abuo-Rahma G.E.A.; Ramadan M.; Abdelrahman M.H.; Pyridazinones and pyrrolones as promising Scaffolds in Medicinal Chemistry. J Adv Biomed Pharm Sci 2019,2(1),19-28
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