Catalysts For Propargylamines Synthesis Via A3, AHA, and KA2 Coupling

Catalysts For Propargylamines Synthesis Via A3, AHA, and KA2 Coupling - A Review

Published:2023-04 Issue:7 Volume:27 Page:621-643
ISSN:1385-2728
Container-title:Current Organic Chemistry
language:en
Short-container-title:COC

Author:

Berrichi Amina¹²^ORCID,Bachir Redouane¹,Bedrane Sumeya¹

Affiliation:

1. Laboratory of Catalysis and Synthesis in Organic Chemistry, University of Abou Bekr Belkaïd, BP 119, Tlemcen, Algeria

2. Institute of Sciences and Technology, Belhadj Bouchaib University, BP 284, 46000 Ain Témouchent, Algeria

Abstract

Abstract: Different intermediates are key molecules to synthesize high-added value bioactive and pharmacology molecules such as propargylamines may be synthesized in several ways using catalysts in homogeneous and heterogeneous conditions. This review presents the catalysts which are used in the A3, AHA, and KA2 coupling reactions to afford propargylamines. It also provides a classification of all the propargylamines known up to date in the literature and their reported synthesis conditions.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry

Reference307 articles.

1. Weinreb O.; Amit T.; Bar-Am O.; Youdim M.B.H.; Rasagiline: A novel anti-Parkinsonian monoamine oxidase-B inhibitor with neuroprotective activity. Prog Neurobiol 2010,92(3),330-344

2. Weinreb O.; Mandel S.; Bar-Am O.; Yogev-Falach M.; Avramovich-Tirosh Y.; Amit T.; Youdim M.B.H.; Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer’s disease drugs. Neurotherapeutics 2009,6(1),163-174

3. Magyar K.; Palfi M.; Jenei V.; Szoko E.; Deprenyl: From chemical synthesis to neuroprotection. Oxidative Stress and Neuroprotection 2006,143-156

4. Youdim M.B.H.; Kupershmidt L.; Amit T.; Weinreb O.; Promises of novel multi-target neuroprotective and neurorestorative drugs for Parkinson’s disease. Parkinsonism Relat Disord 2014,20(Suppl. 1),S132-S136

5. Naoi M.; Maruyama W.; Youdim M.B.H.; Yu P.; Boulton A.A.; Anti-apoptotic function of propargylamine inhibitors of type-B monoamine oxidase. Inflammopharmacology 2003,11(2),175-181

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