Amalgamation and Scrutinizing of Leucine Derivatives Schiff bases Complexes as Antimicrobial Agent

Author:

Pervaiz Muhammad1,Ahmad Ikram2,Saeed Zohaib1,Sagir Muhammad3,Younas Umer4,Tahir Muhammad Bilal3,Ahmad Awais5,Rashid Ayoub1,Syed Quratulain6,Adnan Ahmad1

Affiliation:

1. Department of Chemistry, Government College University, Lahore, Pakistan

2. Department of Chemistry, University of Sahiwal, Sahiwal, Pakistan

3. Department of Chemical Engineering/Physics, Khwaja Fareed University of Engineering and Information Technology, Rahim Yar Khan, Punjab 64200, Punjab, Pakistan

4. Department of Chemistry, The University of Lahore, Lahore, Pakistan

5. Departmento de Quimica Organica, Universidad de Cordoba, Edlificio Marie Curie (C-3), Ctra Nnal IV-A,Km 396,E14014 Cordoba, Spain

6. Pakistan Council of Scientific and industrial Research, Laboratories Complexes (PCSIR) Lahore, Pakistan

Abstract

: The enhanced applications of Schiff bases metal complexes of amino acid derivatives have captured the attention of researchers for the synthesis of leucine derivatives of Schiff bases metal complexes. Amino acids are considered to be essential part of food supplements as well as derivatives of Schiff bases in coordination chemistry due to their donor ability. The leucine derivatives Schiff bases ligand have been synthesized by condensation reaction between amine of leucine with aldehyde or ketone bearing molecules attached with them. These complexes were characterized by different spectroscopic tools in order to confirm their structural geometries. The structural geometries are considered to be very important in order to improve the antimicrobial potential of leucine derivative metal complexes. By taking into account the antimicrobial potential of titled compounds, a comprehensive review of leucine derivatives of Schiff bases metal complexes has been compiled.

Publisher

Bentham Science Publishers Ltd.

Subject

Organic Chemistry,Computer Science Applications,Drug Discovery,General Medicine

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