Aloe vera: An Unconventional Food Used to Reduce Hyperglycemia and Hyperlipidemia: Evidence from Pre-clinical and Clinical Studies

Abstract

The demand for various unconventional foods to reduce the complications in both communicable and non-communicable diseases is increasing day by day. The aim of this review was to observe the efficacy of Aloe vera in hyperglycemia and in hyperlipidemia in vivo (both animals and humans). The studies of different authors were searched by using many scientific search engines such as Pub Med, Google Scholar, Science Direct, the database of Open Access Journals. There are 25 animal studies and 10 human studies included in this review. By analyzing data, data were extracted from selected articles that showed the effects of a different form of Aloe vera on diabetes and hyperlipidemia after consumption. The result of this review covers different doses and forms of Aloe vera, which were provided to target animals and humans for a different duration to achieve an outcome in those articles. Most of the studies showed a significant result that means Aloe vera has a positive effect on diabetes and hyperlipidemia. Further studies are needed to elucidate the pathophysiological mechanisms of action of Aloe vera as well as its efficacy and safety in the treatment of various diseases.