Possible effect of Astaxanthin on obesity related increased COVID-19 infection morbidity and mortality
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Published:2021-10-11
Issue:
Volume:17
Page:
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ISSN:1573-4013
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Container-title:Current Nutrition & Food Science
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language:en
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Short-container-title:CNF
Author:
Örs Elif Didem1ORCID,
Alkan Şenay Burçin1ORCID,
Öksüz Abdullah1ORCID
Affiliation:
1. Necmettin Erbakan University, Faculty of Health Sciences, Department of Nutrition and Dietetics, Konya, Turkey
Abstract
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Obesity is defined by the World Health Organisation (WHO) as a body mass index equals to 30 kg/m2 or greater. It is an important and escalating global public health problem. Obesity is known to cause low-grade chronic inflammation, increasing the burden of noncommunicable and possibly communicable diseases. There is considerable evidence that obesity is associated with an increased risk of contracting coronavirus disease 2019 (COVID-19) infection as well as significantly higher COVID-19 morbidity and mortality. It appears plausible that controlling the chronic systemic low-grade inflammation associated with obesity may have a positive impact on the symptoms and the prognosis of COVID-19 disease in obese patients. Astaxanthin (ASTX) is a naturally occurring carotenoid with anti-inflammatory, antioxidant, and immunomodulatory activities. As a nutraceutical agent, it is used as a preventative and a co-treatment in a number of systemic neurological, cardiovascular, and metabolic diseases. This review article will discuss the pathogenesis of COVID-19 infection and the effect of ASTX on obesity and obesity-related inflammation. The potential positive impact of ASTX anti-inflammatory properties in obese COVID-19 patients will be discussed.
Publisher
Bentham Science Publishers Ltd.
Subject
Public Health, Environmental and Occupational Health,Nutrition and Dietetics,Food Science