Nutraceuticals a Food for Thought in the Treatment of Parkinson’s Disease

Abstract

Background: Brain disorders are presently one of the most serious and challenging health issues in the world. A significant portion of morbidities and fatalities worldwide are caused by these brain disorders. Parkinson's disease (PD) is a neurological condition that develops when dopaminergic neurons are lost in the substantia nigra, causing cognitive and motor impairment. Objectives: Conventional treatment modalities, including dopamine replacement therapy and optimization of dopaminergic transmission approaches, don’t address the pathogenic processes primary to the symptoms of PD and usually become the least essential with time. Researchers are aiming to provide effective treatment in treating PD with minimizing adverse consequences. In the past few years, a number of studies on nutraceuticals have been conducted to produce foods with fewer adverse effects and increased therapeutic effectiveness. The use of these nutraceuticals is typically risk-free and can be coupled with the patient's current common pharmacological therapy to enhance the standard of living and lessen PD symptoms. Conclusion: The current review focuses on a number of important nutritional compounds and dietary changes that have been shown to be effective against a number of the pathogenic pathways involved in the onset and progression of Parkinson's disease (PD), and further lights the justification for their prospect use in the treatment and prevention of PD.