Terpenoids Produced by Plant Endophytic Fungi from Brazil and their Biological Activities: A Review from January 2015 To June 2021

Abstract

Endophytic fungi are fungi that live inside plant tissues at any moment of their life cycle without causing damage or disease symptoms to their hosts. These microorganisms are producers of important substances with several biological activities. Terpenoids are one of the main classes of natural products produced by endophytic fungi, and have a wide range of biological activities, such as anti inflammatory, anticancer, antioxidant, antifungal, antimicrobial, anticholinesterase, antidepressant, antipyretic, antimalarial, among others. Brazil has one of the largest plant reserves on the planet, consisting of an almost untapped source of endophytic fungi. Thus, in this review chapter, we present the results of the research work of Brazilian researchers, with a focus on the isolation and identification of secondary metabolites of the terpenoid class produced by endophytic fungi and their biological activities. The review period includes January 2015 and June 2021.