OPTIMAL METHOD OF PREOPERATIVE DIAGNOSTICS OF PATIENTS WITH CHRONIC PANCREATITIS

Abstract

Abstract. The aim. To determine the best method of preoperative diagnosis of chronic pancreatitis with subsequent correction of the choice of the optimal method of surgical intervention for patients with chronic pancreatitis. Materials and methods. The work presents a thematic review and detailed meta-analysis of literature data from scientific databases “Pub Med”, “Google Scholar”, “Web of Science”, “the Lancet”, “Stanford medicine”, “ResearchGate” and other publications, as well as analysis of our own observations. The results and discussion: Today, modern ideas about the pathogenesis of chronic pancreatitis allow us to understand most of the pathological processes occurring in the pancreas as clearly as possible and lead to the development of chronic pancreatitis. To confirm the diagnosis, we should use a lot of invasive and non-invasive diagnostic methods, which include determining the level of trypsinogen in the blood, chymotrypsin and elastase in the feces, intravenous infusion of cholecystokinin and secretin, magnetic resonance imaging, magnetic resonance cholangiopancreatography, CT scan and modern method like elastography. With analysis of world literary data, as well as analysis of our own experience in the using of preoperative non-invasive methods of diagnosis of chronic pancreatitis, it was found that the most effective and most sensitive methods are elastography and CT scan of the pancreas. Conclusions: The obtained results of CT scan and elastography make it possible to predict and choose the optimal method of surgical intervention in patients with chronic pancreatitis in a short time.