Mucormycosis and its implication in COVID-19

Abstract

Mucormycosis is a life-threatening fungal infection caused by a group of moulds known as mucormycetes. It is a viral disease, increasingly progressive, rapidly triggers in diabetic, immunocompromised and trauma patients. Diabetic patients seem to have the classic rhinocerebral variant. Rhinocerebral mucormycosis begins as a nasal cavity, paranasal sinus, and orbital soft tissue infection. In immunocompetent patients, direct injection also induces cutaneous form. Cutaneous mucormycosis occurs in soft tissue and may infect underlying tissues. Mucormycosis is more frequent in people with major underlying disorders such as diabetic acidosis or acute leukaemia and those taking corticosteroids or cytotoxic drugs. This disease occurs in patients by inhaling fungus spores. Mucormycosis occurs in clinical manifestations. Disseminated mucormycosis is a rare form of mucormycosis, affecting individuals with compromised immune systems. The disease travels to other areas of the body, thereby being prevalent. Brain, core, spleen, eyes, and other organs are among the organs that may be affected. Mucormycosis is a dangerous infection that requires antifungal drugs such as amphotericin B, posaconazole, or isavuconazole. This compilation addresses conceptual background on medicines used to treat mucormycosis, especially in India.