Affiliation:
1. Sri Aurobindo Medical College & PG Institute, Indore, Madhya Pradesh, India
2. S
Abstract
: Adjuvants play an important role in the intraoperative and post-operative analgesia. Spinal Anaesthesia is very common among gynaecological surgeries. Bupivacaine is the most common drug used for in gynaecological surgeries. So, addition of Clonidine or Dexmedetomidine as adjuvant can decrease post-operative analgesia. A randomised controlled trial was done to compare the two groups of Dexmedetomidine and Clonidine along with Bupivacaine. A total of 100 patients were divided into 50 each randomly into two groups and intrathecal medication were given as per the group allotted. : Time of onset of sensory and motor block was much faster in Dexmedetomidine group than Clonidine group. The two segment regression was slower in Dexmedetomidine group compared to Clonidine group. The time taken for two segment regression was 590 ±15 minutes and 361± 18 minutes respectively and was found to be statistically significantOnset of motor block according to Bromage grade 3 was 4.3 ±1.2 minutes and 5.14 ±1.4 among Dexmedetomidine and Clonidine group respectively. The mean values of mean arterial pressures and heart rate were similar throughout the inter operative and post-operative time duration.Planning and managing postoperative analgesia starts from pre anaesthetic evaluation. So Dexmedetomidine when used along with Bupivacaine intrathecally has better postoperative pain relief as compared with Clonidine and Bupivacaine.
Publisher
IP Innovative Publication Pvt Ltd
Reference16 articles.
1. Bubanendran A, Kroin JS, Useful adjuvants for postoperative management.Best Pract Res Clin Anaesthesiol 2007;21(1):31-49
2. International Association for the Study of Pain (IASP). Management of acute pain: a practical guideline. Seattle: International Association for the Study of Pain (IASP),..
3. Warfield CA, Kahn CH, Acute pain management. Programs in U.S. hospitals and experiences and attitudes among U.S. adults.Anesthesiology 1995;83(5):1090-4
4. Lee SH, Kim KH, Cheong SM, Kim S, Kooh M, Chin DK, A comparison of the effect of epidural patient-controlled analgesia with intravenous patient-controlled analgesia on pain control after posterior lumbar instrumented fusion.J Korean Neurosurg Soc 2011;50(3):205-8
5. Manuraj VS, Balaraju TC, Ramdas B, Thankachan S, A comparative study of Bupivacaine and Bupivacaine with clonidine in spinal Anesthesia in patient for Total Abdominal Hysterectomy.J Evol Med Dent Sci 2015;4(15):2427-8