PROBLEMS OF IDENTIFYING PRIMARY IMMUNODEFICIENCY IN CLINICAL PRACTICE

Author:

LEBED' N.1,MAKSIMOV V.2,SOROKINA E.3,KARAKINA M.4,SALIHOVA M.5

Affiliation:

1. FGCUZ "5th Military Clinical Hospital of the National Guard Troops of the Russian Federation"

2. FGCUZ "Military Clinical Hospital of the National Guard Troops of the Russian Federation"

3. I.I. Mechnikov Scientific Research Institute of Vaccines and Serums

4. State Medical Institution of the Sverdlovsk region "Sverdlovsk Regional Clinical Hospital No. 1"

5. Ural State Medical University of the Ministry of Health of the Russian Federation

Abstract

The article deals with difficulties in the diagnostics of primary immunodeficiency in clinical practice and the ways to improve its efficiency on a basis of a clinical case report.

Publisher

Joint Editorial Office of the Ministry of Internal Affairs of Russia

Reference10 articles.

1. Хаитов Р.М. Аллергология и клиническая иммунология / Под ред. Р.М. Хаитова, Н.И. Ильиной. – Москва. – ГЭОТАР-Медиа. – 2019. – 336 с., Haitov R.M. Allergologiya i klinicheskaya immunologiya / Pod red. R.M. Haitova, N.I. Il'inoy. – Moskva. – GEOTAR-Media. – 2019. – 336 s.

2. Tangye S.G., Al-Herz W., Bousfiha A. et al. Human inborn errors of immunity: 2019 update on the classification from the International Union of Immunological Societies Expert Committee. J Clin Immunol. – 2020. 40:24–64., Tangye S.G., Al-Herz W., Bousfiha A. et al. Human inborn errors of immunity: 2019 update on the classification from the International Union of Immunological Societies Expert Committee. J Clin Immunol. – 2020. 40:24–64.

3. The 2022 Update of IUIS Phenotypical Classification for Human Inborn Errors of Immunity J Clin Immunol. – 2022 Oct; 42(7):1508–1520. doi: 10.1007/s10875-022-01352-z, The 2022 Update of IUIS Phenotypical Classification for Human Inborn Errors of Immunity J Clin Immunol. – 2022 Oct; 42(7):1508–1520. doi: 10.1007/s10875-022-01352-z

4. Meyts I., Bousfiha A., Duff C., Singh S., Lau Y.L., Condino-Neto A., Bezrodnik L., Ali A., Adeli M., Drabwell J. Primary Immunodeficiencies: A Decade of Progress and a Promising Future. Front Immunol. – 2021 Feb 18; 11:625753. doi: 10.3389/fimmu.2020.625753, Meyts I., Bousfiha A., Duff C., Singh S., Lau Y.L., Condino-Neto A., Bezrodnik L., Ali A., Adeli M., Drabwell J. Primary Immunodeficiencies: A Decade of Progress and a Promising Future. Front Immunol. – 2021 Feb 18; 11:625753. doi: 10.3389/fimmu.2020.625753

5. Bousfiha A.A., Jeddane L., Ailal F., Benhsaien I., Mahlaoui N., Casanova J.L., Abel L. Primary immunodeficiency diseases worldwide: more common than generally thought. J Clin Immunol. – 2013 Jan; 33(1):1–7. doi: 10.1007/s10875-012-9751-7, Bousfiha A.A., Jeddane L., Ailal F., Benhsaien I., Mahlaoui N., Casanova J.L., Abel L. Primary immunodeficiency diseases worldwide: more common than generally thought. J Clin Immunol. – 2013 Jan; 33(1):1–7. doi: 10.1007/s10875-012-9751-7

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