Epileptic seizures caused by hypoxic-ischemic damage to the central nervous system

Abstract

Epilepsy is a chronic disease of the brain. There are many risk factors and causes of this disease, but it is known that the peak incidence occurs in the first year of a child's life. This is due to the fact that this pathology in most cases is the outcome of perinatal damage to the central nervous system (CNS), which has a hypoxic-ischemic genesis. Hemodynamic disturbances that occur in hypoxia lead to various metabolic shifts, which is subsequently accompanied by neuronal damage and reduced inhibitory influence over all processes. Based on the analysis of literature data, we studied the mechanisms of development of this disease, peculiarities of its course, and differential diagnostic features of epileptic seizures caused by hypoxic-ischemic CNS lesions.