Early and long-term neurological complications of chemotherapy in oncology (literature review)

Author:

Vykhovanets N.  Yu.1,Alyoshechkin P.  A.1,Tomash L.  A.1,Shevchenko A.  S.1,Krasnyanskaya L.  A.2,Shulik A.  I.1

Affiliation:

1. Donetsk National Medical University Named after M. Gorky

2. “Energetik” Municipal Clinical Hospital No. 2

Abstract

An analysis of the clinical manifestations of complications caused by the toxic effect of chemotherapeutic drugs used in the treatment of malignant neoplasms was carried out. The variety of clinical symptoms that develop against the background of chemotherapy for malignant neoplasms leads to difficulties in differential diagnosis of a primary neurological disease and the identification of complications during treatment. The severity of these complications depends on a number of factors, including the drug used, its dosage and duration of use, the use of various methods of combination therapy and radiation methods, as well as the presence of comorbid pathology in patients. A clear understanding of the mechanisms of development of neurotoxicity and timely diagnosis of such conditions is a priority task of modern clinical medicine Modern methods of treating patients with malignant neoplasms should be based on a multidisciplinary medical approach, including a set of measures to prevent unwanted toxic effects of treatment, stratify individual mortality risks and develop methods of rehabilitation and medical examination.

Publisher

Russian Society of Clinical Oncology

Subject

General Agricultural and Biological Sciences

Reference37 articles.

1. Kovtun O.P., Bazarnyi V. V., Koryakina O. V., Abdullaev A. N. Khimioterapiya neirotoksicheskikh oslozhnenii u detei. Obzor literatury. Pediatricheskaya farmakologiya. 2020 ; 17 (1) : 12–17. https://doi.org/10.15690/pf.v17i1.2077.

2. Linkov, M. V. Khimioindutsirovannye polinevropatii kak oslozhnenie terapii mnozhestvennoi mielomy / M. V. Linkov, N. N. Usova // Meditsinskie novosti .– 2021 .– № 1 (316) .– S. 37–39.

3. Fedyanin M.Yu., El'snukaeva Kh. Kh., Pokataev I. A., Tryakin A. A., Bulanov A. A., Sekhina O. V., Chekini D. A., Ignatova E. O., Gordeev S. S., Budurova M. D., Mamedli Z., Podluzhnyi D. V., Kozlov N. A., Tyulyandin S. A. Effektivnost' oksaliplatinsoderzhashchikh rezhimov khimioterapii 1-i linii v zavisimosti ot mutatsionnogo statusa gena KRAS. Tazovaya khirurgiya i onkologiya. 2018 ; 8 (1) : 34–41. https://doi.org/10.17650/2220-3478-2018-8-1-34-41.

4. Orlova O.L., Nikolaeva L. L., Korol' L. A., Dmitrieva M. V., Polozkova A. P., Lantsova A. V., Gulyakin I. D., Oborotova N. A. SOVREMENNYE ONKOPREPARATY DLYa VNUTRENNEGO PRIMENENIYa. Farmatsiya i farmakologiya. 2018 ; 6 (5) : 440–461. https://doi.org/10.19163/2307-9266-2018-6-5-440-461.

5. Sakaeva, D. D. Peroral'naya khimioterapiya vinorelbinom pri rasprostranennom rake molochnoi zhelezy : ee rol' v klinicheskoi praktike / D. D. Sakaeva, A. F. Nasretdinov // Farmateka .– 2019 .– T. 26 .– № 7 .– S. 96–101. DOI : 10.18565/pharmateca.2019.7.96–101.

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3