Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody

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Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates

Published:2016-11-09 Issue:1 Volume:16 Page:116-123
ISSN:1535-7163
Container-title:Molecular Cancer Therapeutics
language:en
Short-container-title:Mol Cancer Ther

Author:

Burke Patrick J.,Hamilton Joseph Z.,Jeffrey Scott C.,Hunter Joshua H.,Doronina Svetlana O.,Okeley Nicole M.,Miyamoto Jamie B.,Anderson Martha E.,Stone Ivan J.,Ulrich Michelle L.,Simmons Jessica K.,McKinney Erica E.,Senter Peter D.,Lyon Robert P.

Publisher

American Association for Cancer Research (AACR)

Subject

Cancer Research,Oncology

Cited by 109 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Optimization of a pendant-shaped PEGylated linker for antibody-drug conjugates;Journal of Controlled Release;2024-11

2. Structure–Activity Relationship of Antibody–Oligonucleotide Conjugates: Evaluating Bioconjugation Strategies for Antibody–siRNA Conjugates for Drug Development;Journal of Medicinal Chemistry;2024-08-28

3. Synthesis and evaluation of antibody-drug conjugates with high drug-to-antibody ratio using dimaleimide-DM1 as a linker- payload;Bioorganic Chemistry;2024-08

4. Targeted Drug Conjugates in Cancer Therapy: Challenges and Opportunities;Pharmaceutical Science Advances;2024-08

5. Homogeneous multi-payload antibody–drug conjugates;Nature Chemistry;2024-05-17

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