RAS at 40: Update from the RAS Initiative
Author:
Affiliation:
1. 1Frederick National Laboratory for Cancer Research, Frederick, Maryland.
2. 2University of California, San Francisco, San Francisco, California.
Abstract
Funder
NCI NIH
Publisher
American Association for Cancer Research (AACR)
Subject
Oncology
Link
https://aacrjournals.org/cancerdiscovery/article-pdf/12/4/895/3108005/895.pdf
Reference8 articles.
1. Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity;Maurer;Proc Natl Acad Sci U S A,2012
2. Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation;Sun;Angew Chem Int Ed Engl,2012
3. Structural basis of recognition of farnesylated and methylated KRAS4b by PDEdelta;Dharmaiah;Proc Natl Acad Sci U S A,2016
4. Structural insights into the SPRED1-neurofibromin-KRAS complex and disruption of SPRED1-neurofibromin interaction by oncogenic EGFR;Yan;Cell Rep,2020
5. KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation;Tran;Nat Commun,2021
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Synergistic anti-tumor activity, reduced pERK, and immuno-stimulatory cytokine profiles with 5-FU or ONC212 plus KRAS G12D inhibitor MRTX1133 in CRC and pancreatic cancer cells independent of G12D mutation;2023-09-17
2. Endogenous oncogenic KRAS expression increases cell proliferation and motility in near-diploid hTERT RPE-1 cells;2023-09-08
3. RAS signaling and immune cells: a sinister crosstalk in the tumor microenvironment;Journal of Translational Medicine;2023-09-05
4. RAS GTPases and Interleaflet Coupling in the Plasma Membrane;Cold Spring Harbor Perspectives in Biology;2023-07-18
5. RAS G-domains fine-tune the sorting of phosphatidylserine acyl chains in the plasma membrane;2023-06-22
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3