MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia-Reference-Cited by-同舟云学术

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MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia

Published:2021-09-30 Issue:22 Volume:81 Page:5733-5744
ISSN:0008-5472
Container-title:Cancer Research
language:en
Short-container-title:Cancer Res

Author:

Sanjiv Kumar,Calderón-Montaño José Manuel^ORCID,Pham Therese M.,Erkers Tom,Tsuber Viktoriia,Almlöf Ingrid,Höglund Andreas,Heshmati Yaser,Seashore-Ludlow Brinton^ORCID,Nagesh Danda Akhilesh,Gad Helge^ORCID,Wiita Elisee,Göktürk Camilla^ORCID,Rasti Azita,Friedrich Stefanie^ORCID,Centio Anders,Estruch Montserrat^ORCID,Våtsveen Thea Kristin,Struyf Nona^ORCID,Visnes Torkild^ORCID,Scobie Martin,Koolmeister Tobias,Henriksson Martin,Wallner Olov,Sandvall Teresa,Lehmann Sören,Theilgaard-Mönch Kim^ORCID,Garnett Mathew J.^ORCID,Östling Päivi,Walfridsson Julian,Helleday Thomas,Warpman Berglund Ulrika^ORCID

Funder

The European Research Council

The Swedish Research Council

The Swedish Cancer Society

Swedish Foundation for Strategic Research

Radiumhemmets Forskningsfond

The Swedish Childhood Cancer

Vinnov

The Swedish Institute Visby and Danish Cancer Society

Wellcome Trust

Publisher

American Association for Cancer Research (AACR)

Subject

Cancer Research,Oncology

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. MTH1 inhibition synergizes with ROS-inducing agents to trigger cervical cancer cells undergoing parthanatos;Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease;2024-06

2. Mitotic MTH1 inhibitor TH1579 induces PD-L1 expression and inflammatory response through the cGAS-STING pathway;Oncogenesis;2024-05-25

3. Oxidative stress is two‐sided in the treatment of acute myeloid leukemia;Cancer Medicine;2024-05

4. Role of reactive oxygen species in myelodysplastic syndromes;Cellular & Molecular Biology Letters;2024-04-14

5. Targeting MutT Homolog 1 (MTH1) for Breast Cancer Suppression by Using a Novel MTH1 Inhibitor MA−24 with Tumor-Selective Toxicity;Pharmaceuticals;2024-02-23

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