Local Anesthetics: Review of Pharmacological Considerations

Author:

Becker Daniel E1,Reed Kenneth L2

Affiliation:

1. Associate Director of Education, General Dental Practice Residency, Miami Valley Hospital, Dayton, Ohio

2. Assistant Director and Attending Dentist in Anesthesia, Advanced Education in General Dentistry, Attending Dentist in Anesthesia, Graduate Pediatric Dentistry and Dental Anesthesiology, Lutheran Medical Center, Brooklyn, New York, Clinical Associate Professor, Endodontics, Oral and Maxillofacial Surgery and Orthodontics, The Herman Ostrow School of Dentistry of the University of Southern Californ

Abstract

Local anesthetics have an impressive history of efficacy and safety in medical and dental practice. Their use is so routine, and adverse effects are so infrequent, that providers may understandably overlook many of their pharmacotherapeutic principles. The purpose of this continuing education article is to provide a review and update of essential pharmacology for the various local anesthetic formulations in current use. Technical considerations will be addressed in a subsequent article.

Publisher

American Dental Society of Anesthesiology (ADSA)

Subject

Anesthesiology and Pain Medicine

Reference38 articles.

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4. Factors affecting plasma levels of lignocaine and prilocaine;Scott;Brit J Anaesth,1972

5. The pharmacokinetics and cardiovascular effects of high-dose articaine with 1 ∶ 100,000 and 1 ∶ 200,000 epinephrine;Hersh;J Am Dent Assoc,2006

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