Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production

Author:

Guido Carmela,Whitaker-Menezes Diana,Capparelli Claudia,Balliet Renee,Lin Zhao,Pestell Richard G.,Howell Anthony,Aquila Saveria,Andò Sebastiano,Martinez-Outschoorn Ubaldo,Sotgia Federica,Lisanti Michael P.

Publisher

Informa UK Limited

Subject

Cell Biology,Developmental Biology,Molecular Biology

Reference49 articles.

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3. Induction of alpha-smooth muscle actin by transforming growth factor-beta 1 in quiescent human breast gland fibroblasts. Implications for myofibroblast generation in breast neoplasia;Rønnov-Jessen;Lab Invest,1993

4. Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts;Desmoulière;J Cell Biol,1993

5. Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma;Löhr;Cancer Res,2001

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