Clinical guidelines for cryoprecipitate transfusions-Reference-Cited by-同舟云学术

Clinical guidelines for cryoprecipitate transfusions

Published:2020-03-11 Issue:1 Volume:65 Page:87-114
ISSN:2411-3042
Container-title:Russian journal of hematology and transfusiology
language:
Short-container-title:Gematologiâ i transfuziologiâ

Author:

Galstyan G. M.¹^ORCID,Gaponova T. V.¹^ORCID,Zhiburt E. B.²^ORCID,Balashova E. N.³^ORCID,Berkovskiy A. L.¹^ORCID,Bystrykh O. A.³^ORCID,Kupryashov A. A.⁴^ORCID,Olovnikova N. I.¹^ORCID,Oshorov A. V.⁵^ORCID,Rybka M. M.⁴^ORCID,Troitskaya V. V.¹^ORCID,Bulanov A. Yu.⁶,Zhuravel S. V.⁷^ORCID,Lubnin A. Yu.⁵^ORCID,Mazurok V. A.⁸^ORCID,Nedomolkin S. V.⁹^ORCID,Pevtcov D. E.¹⁰^ORCID,Rogachevskiy O. V.³^ORCID,Salimov E. L.¹¹^ORCID,Trakhtman P. E.¹²^ORCID,Chzhao A. V.¹³^ORCID,Sherstnev F. S.¹⁴^ORCID,Savchenko V. G.¹^ORCID

Affiliation:

1. National Research Center for Hematology

2. Pirogov National Medical and Surgical Center

3. V.I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology

4. Bakoulev Scientific Center for Cardiovascular Surgery

5. Burdenko Neurosurgery Institute

6. Moscow City municipal hospital 52

7. N.V. Sklifosovsky Research Institute of Emergency Medicine

8. Almazov National Medical Research Centre

9. S.M. Kirov Military Medical Academy

10. I.P. Pavlov First Saint Petersburg State Medical University

11. I.M. Sechenov First Moscow State Medical University

12. Dmitry Rogachev National Research Center of Pediatric Hematology, Oncology and Immunology

13. A.V. Vishnevsky National Medical Research Center of Surgery

14. Kirov Research Institute of Hematology and Blood Transfusion

Abstract

Background. Cryoprecipitate is made from fresh-frozen plasma (FFP) and contains ﬁbrinogen, factor VIII, factor XIII, von Willebrand factor, ﬁbronectin and ﬁbrinogen.Aim. To provide information on the composition and methods of production, storage, transportation and clinical use of cryoprecipitate.General ﬁndings. Cyoprecipitate is manufactured by slowly thawing FFP at 1–6°C. This precipitates out cryoproteins: factor VIII, von Willebrand factor, factor XIII, ﬁbronectin and ﬁbrinogen. After centrifugation, the cryoproteins are resuspended in a reduced volume of plasma. Cryoprecipitate is stored at temperatures not exceeding –25° С for 36 months. Indications for cryoprecipitate transfusion are hemophilia A, von Willebrand disease, factor XIII deﬁciency, congenital aﬁbrinogenemia and hypoﬁbrinogenemia, acquired hypoﬁbrinogenemia. These indications can occur in obstetrics, neonatology, cardiac surgery, neurosurgery, hematology, orthopaedics, and general surgery during liver transplantation and disseminated intravascular coagulation.

Publisher

National Medical Research Center of Hematology of the Ministry of Health of the Russian Federation

Subject

Hematology

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