Clinical case of neonatal lupus with cartilaginous metaplasia, fibrosis and calcification of the atrioventricular node zone

Author:

Davydov D. A.1ORCID,Makarov I. A.2ORCID,Morozov A. A.2ORCID,Makarova T. A.2ORCID,Mitrofanova L. B.2

Affiliation:

1. Pavlov First Saint Petersburg State Medical University of the Ministry of Health of the Russian Federation

2. Almazov National Medical Research Center” of the Ministry of Health of the Russian Federation

Abstract

Neonatal lupus is a rare disease associated with the circulation in the mother’s blood of one or more autoantibodies to soluble intracellular ribonucleoproteins Ro/SS-A and La/SS-B. This disease is extremely often manifested by congenital heart block, which can progress even after the birth of a child. We have described a case of fibrosis, calcification and cartilaginous metaplasia of the atrioventricular node zone, which caused complete atrioventricular block in a child who died from neonatal lupus.

Publisher

Institute of Cardio Technics - INCART

Subject

Pharmacology (medical),Cardiology and Cardiovascular Medicine,Emergency Medicine

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