Abstract
Objective: The objective of this study is to analyze the action of Melaleuca essential oil emulsion on two isolates of Klebsiella pneumoniae as a new alternative.
Theoretical Framework: K. pneumoniae resistance to antibiotics is an urgent public health problem. Melaleuca alternifolia oil appears as a promising therapeutic alternative, with potential to combat the bacteria.
Method: The methodology adopted for this research includes evaluating the minimum inhibitory concentration of the isolates, evaluating the elimination time of microorganisms by Time kill curve, biofilm formation and biofilm eradication.
Results and Discussion: The results obtained revealed that Melaleuca alternifolia oil together with a bioemulsifier appears as a promising therapeutic alternative, with the potential to combat the bacteria and save lives. More research is needed, but the future of medicine against bacterial resistance may lie in the power of nature.
Implications of the Research: The research demonstrates the effectiveness of Melaleuca essential oil emulsion together with a bioemulsifier in combating multi-resistant Klebsiella pneumoniae. This discovery is crucial for public health as it offers a promising alternative to traditional antibiotics, which are becoming increasingly less effective due to bacterial resistance.
Originality/Value: Research on Melaleuca essential oil emulsion together with a bioemulsifier to combat multi-resistant Klebsiella pneumoniae presents significant originality and value for public health.
Publisher
RGSA- Revista de Gestao Social e Ambiental
Reference55 articles.
1. Adeolu, A. O. (2016). Klebsiella pneumoniae: A versatile pathogen in both community and hospital settings. Journal of Hospital Infection, 103(2), 160-166.
2. Ali Sam, Sayyed RZ, Mir MI, Khan MY, Hameeda B, Alkhanani MF, Haque S, Mohammad Al Tawaha AR, Poczai P. Induction of Systemic Resistance in Maize and Antibiofilm Activity of Surfactin From Bacillus velezensis MS20. Front Microbiol. 2022 May 9;13:879739. doi: 10.3389/fmicb.2022.879739.
3. Amin, Catarina Epichin et al. Fatores determinantes na infecção hospitalar por klebsiella pneumoniae resistente a carbapenêmicos. Brazilian Journal of Health Review, v. 3, n. 5, p. 14320-14333, 2020.
4. Araujo, J. et al., (2022). Surface-active compounds produced by microorganisms: promising molecules for the development of antimicrobial, anti-inflammatory, and healing agents. Antibiotics, 11(8), 1106.
5. Aslam, Bilal et al. Antibiotic resistance: a rundown of a global crisis. Infection and drug resistance, p. 1645-1658, 2018.