Susceptibility Analysis of Klebsiella Pneumoniae Strains to Team Essential Oil Emulsion and Surface Active Compounds

Abstract

Objective: The objective of this study is to analyze the action of Melaleuca essential oil emulsion on two isolates of Klebsiella pneumoniae as a new alternative.   Theoretical Framework: K. pneumoniae resistance to antibiotics is an urgent public health problem. Melaleuca alternifolia oil appears as a promising therapeutic alternative, with potential to combat the bacteria.   Method: The methodology adopted for this research includes evaluating the minimum inhibitory concentration of the isolates, evaluating the elimination time of microorganisms by Time kill curve, biofilm formation and biofilm eradication.   Results and Discussion: The results obtained revealed that Melaleuca alternifolia oil together with a bioemulsifier appears as a promising therapeutic alternative, with the potential to combat the bacteria and save lives. More research is needed, but the future of medicine against bacterial resistance may lie in the power of nature.   Implications of the Research: The research demonstrates the effectiveness of Melaleuca essential oil emulsion together with a bioemulsifier in combating multi-resistant Klebsiella pneumoniae. This discovery is crucial for public health as it offers a promising alternative to traditional antibiotics, which are becoming increasingly less effective due to bacterial resistance.   Originality/Value: Research on Melaleuca essential oil emulsion together with a bioemulsifier to combat multi-resistant Klebsiella pneumoniae presents significant originality and value for public health.