Cdc14-Dependent Dephosphorylation of a Kinetochore Protein Prior to Anaphase in Saccharomyces cerevisiae-Reference-Cited by-同舟云学术

Cdc14-Dependent Dephosphorylation of a Kinetochore Protein Prior to Anaphase in Saccharomyces cerevisiae

Published:2010-12-01 Issue:4 Volume:186 Page:1487-1491
ISSN:1943-2631
Container-title:Genetics
language:en
Short-container-title:

Author:

Akiyoshi Bungo¹²,Biggins Sue¹

Affiliation:

1. Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109 and

2. Molecular and Cellular Biology Program, University of Washington, Seattle, Washington 98195

Abstract

Abstract The budding yeast Cdc14 phosphatase reverses Cdk1 phosphorylation to promote mitotic exit. Although Cdc14 activity is thought to be restricted to anaphase, we found that dephosphorylation of the Dsn1 kinetochore protein in metaphase requires Cdc14. These data suggest that there is a nonnucleolar pool of active Cdc14 prior to anaphase.

Publisher

Oxford University Press (OUP)

Subject

Genetics

Link

https://academic.oup.com/genetics/article-pdf/186/4/1487/42177088/genetics1487.pdf

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