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ASO Author Reflections: The Challenging Journey from cCR to pCR After Neoadjuvant Treatment for Esophageal Squamous Cell Carcinoma

  • ASO Author Reflections
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References

  1. Wu YY, Dai L, Yang YB, et al. Long-term survival and recurrence patterns in locally advanced esophageal squamous cell carcinoma patients with pathologic complete response after neoadjuvant chemotherapy followed by surgery. Ann Surg Oncol. 2024. https://doi.org/10.1245/s10434-023-14809-1.

    Article  PubMed  Google Scholar 

  2. Sung H, Ferlay J, Siegel RL, et al. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–49.

    Article  PubMed  Google Scholar 

  3. Arnold M, Soerjomataram I, Ferlay J, et al. Global incidence of oesophageal cancer by histological subtype in 2012. Gut. 2015;64(3):381–7.

    Article  PubMed  Google Scholar 

  4. Zeng H, Zheng R, Guo Y, et al. Cancer survival in China, 2003–2005: a population-based study. Int J Cancer. 2015;136(8):1921–30.

    Article  CAS  PubMed  Google Scholar 

  5. Teniere P, Hay JM, Fingerhut A, et al. Postoperative radiation therapy does not increase survival after curative resection for squamous cell carcinoma of the middle and lower esophagus as shown by a multicenter controlled trial. French University Association for Surgical Research. Surg Gynecol Obstet. 1991;173(2):123–30.

    CAS  PubMed  Google Scholar 

  6. Pouliquen X, Levard H, Hay JM, et al. 5-Fluorouracil and cisplatin therapy after palliative surgical resection of squamous cell carcinoma of the esophagus. A multicenter randomized trial. French Associations for Surgical Research. Ann Surg. 1996;223(2):127–33.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  7. Arnott SJ, Duncan W, Gignoux M, et al. Oeosphageal cancer collaborative group. Preoperative radiotherapy for esophageal carcinoma. Cochrane Database Syst Rev. 2005;4:CD001799.

    Google Scholar 

  8. Medical Research Council Oesophageal Cancer Working Group. Surgical resection with or without preoperative chemotherapy in oesophageal cancer: a randomised controlled trial. Lancet. 2002;359(9319):1727–33.

    Article  Google Scholar 

  9. van Hagen P, Hulshof MC, van Lanschot JJ, et al. Preoperative chemoradiotherapy for esophageal or junctional cancer. N Engl J Med. 2012;366(22):2074–84.

    Article  PubMed  Google Scholar 

  10. Yang H, Liu H, Chen Y, et al. Neoadjuvant chemoradiotherapy followed by surgery versus surgery alone for locally advanced squamous cell carcinoma of the esophagus (NEOCRTEC5010): a phase III multicenter, randomized, open-label clinical trial. J Clin Oncol. 2018;36(27):2796–803.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Liu Y, Wang Y, Iannessi A. The adjudication rates between readers in Blinded Independent Central Review (BICR) of advanced esophageal cancer trials with or without immune checkpoint initiators as first-line therapy. J Clin Oncol. 2022;40(16_suppl):4039.

    Article  Google Scholar 

  12. Lowe VJ, Booya F, Fletcher JG, et al. Comparison of positron emission tomography, computed tomography, and endoscopic ultrasound in the initial staging of patients with esophageal cancer. Mol Imaging Biol. 2005;7(6):422–30.

    Article  PubMed  Google Scholar 

  13. Swisher SG, Maish M, Erasmus JJ, et al. Utility of PET, CT, and EUS to identify pathologic responders in esophageal cancer. Ann Thorac Surg. 2004;78(4):1152–60.

    Article  PubMed  Google Scholar 

  14. de Gouw DJJM, Klarenbeek BR, et al. Detecting pathological complete response in esophageal cancer after neoadjuvant therapy based on imaging techniques: a diagnostic systematic review and meta-analysis. J Thorac Oncol. 2019;14(7):1156–71.

    Article  PubMed  Google Scholar 

  15. Lee SL, Yadav P, Starekova J, et al. Diagnostic performance of MRI for esophageal carcinoma: a systematic review and meta-analysis. Radiology. 2021;299(3):583–94.

    Article  PubMed  Google Scholar 

  16. Pellat A, Dohan A, Soyer P, Veziant J, Coriat R, Barret M. The role of magnetic resonance imaging in the management of esophageal cancer. Cancers (Basel). 2022;14(5):1141.

    Article  PubMed  Google Scholar 

  17. van Westreenen HL, Westerterp M, Bossuyt PM, et al. Systematic review of the staging performance of 18F-fluorodeoxyglucose positron emission tomography in esophageal cancer. J Clin Oncol. 2004;22(18):3805–12.

    Article  PubMed  Google Scholar 

  18. Luo LN, He LJ, Gao XY, Huang XX, Shan HB, Luo GY, Li Y, Lin SY, Wang GB, Zhang R, Xu GL, Li JJ. Endoscopic ultrasound for preoperative esophageal squamous cell carcinoma: a meta-analysis. PLoS One. 2016;11(7):e0158373.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Yang J, Luo GY, Liang RB, et al. Efficacy of endoscopic ultrasonography for determining clinical t category for esophageal squamous cell carcinoma: data from 1434 surgical cases. Ann Surg Oncol. 2018;25(7):2075–82.

    Article  PubMed  Google Scholar 

  20. Zhang X, Watson DI, Lally C, Bessell JR. Endoscopic ultrasound for preoperative staging of esophageal carcinoma. Surg Endosc. 2005;19(12):1618–21.

    Article  CAS  PubMed  Google Scholar 

  21. Shimada H, Fukagawa T, Haga Y, et al. Clinical TNM staging for esophageal, gastric, and colorectal cancers in the era of neoadjuvant therapy: a systematic review of the literature. Ann Gastroenterol Surg. 2021;5(4):404–18.

    Article  PubMed  PubMed Central  Google Scholar 

  22. Noordman BJ, Spaander MCW, Valkema R, et al. Detection of residual disease after neoadjuvant chemoradiotherapy for oesophageal cancer (preSANO): a prospective multicentre, diagnostic cohort study. Lancet Oncol. 2018;19(7):965–74.

    Article  PubMed  Google Scholar 

  23. Zhang X, Eyck BM, Yang Y, et al. Accuracy of detecting residual disease after neoadjuvant chemoradiotherapy for esophageal squamous cell carcinoma (preSINO trial): a prospective multicenter diagnostic cohort study. BMC Cancer. 2020;20(1):194.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Liu Z, Yang Y, Liu J, et al. Circulating tumor DNA (ctDNA) in predicting residual disease after neoadjuvant chemoradiotherapy (nCRT) for esophageal squamous cell carcinoma (ESCC). J Clin Oncol. 2022;40(16_suppl):4044.

    Article  Google Scholar 

  25. T F. The first successful resection of the thoracic portion of the esophagus for carcinoma. Surg Gynecol Obstet. 1913;16:614–7.

    Google Scholar 

  26. Fujita H. Anesthesia of Torek’s operation: the first successful resection of a cancer in the thoracic esophagus-an abridged translation of an essay in Japanese. Gen Thorac Cardiovasc Surg. 2017;65(2):80–4.

    Article  PubMed  Google Scholar 

  27. Finks JF, Osborne NH, Birkmeyer JD. Trends in hospital volume and operative mortality for high-risk surgery. N Engl J Med. 2011;364(22):2128–37.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

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Funding

The Funding was provided by the Beijing Municipal Administration of Hospitals Special Fund for Digestive System Multidisciplinary Synergic Development (Grant Number: XXT018).

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Authors and Affiliations

  1. State Key Laboratory of Molecular Oncology, Beijing Key Laboratory of Carcinogenesis and Translational Research, Thoracic Surgery of Department, Peking University Cancer Hospital and Institute, Beijing, 100142, China

    Ke-Neng Chen MD, PhD

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  1. Ke-Neng Chen MD, PhD
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Correspondence to Ke-Neng Chen MD, PhD.

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This article refers to: Wu YY, Dai L, Yang YB, et al. Long-term survival and recurrence patterns in locally advanced esophageal squamous cell carcinoma patients with pathologic complete response after neoadjuvant chemotherapy followed by surgery. Annals Surgical Oncology. (2024). https://doi.org/10.1245/s10434-023-14809-1.

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Chen, KN. ASO Author Reflections: The Challenging Journey from cCR to pCR After Neoadjuvant Treatment for Esophageal Squamous Cell Carcinoma. Ann Surg Oncol (2024). https://doi.org/10.1245/s10434-024-15035-z

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  • DOI: https://doi.org/10.1245/s10434-024-15035-z

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