Management of rectal cancer in the era of total neoadjuvant therapy and watch and wait: A multidisciplinary team discussion at the Australasian Gastro‐Intestinal Trials Group (AGITG) Annual Scientific Meeting 2022

Author:

Jain Ankit12ORCID,Gormly Kirsten L.34ORCID,Glyn Tamara5ORCID,Sammour Tarik67ORCID,Koay Eugene J.8ORCID,Oar Andrew9ORCID,Jameson Michael B.1011ORCID,Smyth Elizabeth C.12,Vatandoust Sina1314ORCID

Affiliation:

1. Department of Medical Oncology The Canberra Hospital Garran Australian Capital Territory Australia

2. ANU Medical School Australian National University Canberra Australian Capital Territory Australia

3. Jones Radiology Eastwood South Australia Australia

4. The University of Adelaide Adelaide South Australia Australia

5. Department of Surgery and Critical Care University of Otago Christchurch New Zealand

6. School of Medicine The University of Adelaide Adelaide South Australia Australia

7. Department of Surgery Royal Adelaide Hospital Adelaide South Australia Australia

8. Department of Gastrointestinal Radiation Oncology The University of Texas MD Anderson Cancer Center Houston Texas USA

9. Icon Cancer Centre Gold Coast University Hospital Southport Queensland Australia

10. Regional Cancer Centre Waikato Hospital Hamilton New Zealand

11. Waikato Clinical Campus, Faculty of Medical and Health Sciences University of Auckland Hamilton New Zealand

12. Department of Oncology Cambridge University Hospitals NHS Foundation Trust Cambridge UK

13. Department of Medical Oncology Flinders Medical Centre Bedford Park Australia

14. College of Medicine and Public Health Flinders University Bedford Park Australia

Abstract

AbstractRectal cancer is a common malignancy. The management of rectal cancer has recently evolved and has undergone a paradigm shift with the advent of treatment approaches such as total neoadjuvant therapy and the watch‐and‐wait approach. However, despite the recently available evidence, there is no consensus on the optimal management approach in the setting of locally advanced rectal cancer. To address some of the controversies, a joint multidisciplinary panel discussion was conducted at the Australasian Gastro‐Intestinal Trials Group (AGITG) Annual Scientific Meeting in November 2022. Members from different subspecialties formed two panels and discussed three clinical cases in a debate format. Each case represented some of the complex issues faced by clinicians in this setting. The discussion is now presented in this manuscript, which depicts the different available management approaches and reiterates the importance of a multidisciplinary approach.

Publisher

Wiley

Subject

Oncology,General Medicine

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