Simvastatin alleviates airway inflammation and remodelling through up-regulation of autophagy in mouse models of asthma

Author:

Gu Wen1ORCID,Cui Rong2,Ding Tao3,Li Xiaoming1,Peng Juan1,Xu Weiguo1,Han Fengfeng1,Guo Xuejun1

Affiliation:

1. Department of Respiratory Medicine; Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine; Shanghai China

2. Department of Gastrointestinal Surgery; Jiading Hospital of Traditional Chinese Medicine; Shanghai China

3. Department of Respiratory Medicine; People's Hospital of Rizhao; Rizhao China

Funder

National Natural Sciences Foundation of China

Publisher

Wiley

Subject

Pulmonary and Respiratory Medicine

Reference33 articles.

1. The role of allergy in the development of asthma;Holt;Nature,1999

2. Remodeling in asthma and chronic obstructive lung disease;Jeffery;Am. J. Respir. Crit. Care Med.,2001

3. Airway structural alterations selectively associated with severe asthma;Benayoun;Am. J. Respir. Crit. Care Med.,2003

4. Remodeling in asthma;Al-Muhsen;J. Allergy Clin. Immunol.,2011

5. Airway smooth muscle in airway reactivity and remodeling: what have we learned?;Prakash;Am. J. Physiol. Lung Cell. Mol. Physiol.,2013

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