The respiratory depressant effects of mitragynine are limited by its conversion to 7‐OH mitragynine-Reference-Cited by-同舟云学术

The respiratory depressant effects of mitragynine are limited by its conversion to 7‐OH mitragynine

Published:2022-03-30 Issue:14 Volume:179 Page:3875-3885
ISSN:0007-1188
Container-title:British Journal of Pharmacology
language:en
Short-container-title:British J Pharmacology

Author:

Hill Rob¹²,Kruegel Andrew C.³,Javitch Jonathan A.⁴⁵,Lane J. Robert¹²^ORCID,Canals Meritxell¹²^ORCID

Affiliation:

1. Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre University of Nottingham Nottingham UK

2. Centre of Membrane Proteins and Receptors Universities of Nottingham and Birmingham Midlands UK

3. Department of Chemistry Columbia University New York New York USA

4. Departments of Psychiatry and Molecular Pharmacology and Therapeutics Columbia University Vagelos College of Physicians and Surgeons New York New York USA

5. Division of Molecular Therapeutics New York State Psychiatric Institute New York New York USA

Funder

Biotechnology and Biological Sciences Research Council

Hope for Depression Research Foundation

Academy of Medical Sciences

Publisher

Wiley

Subject

Pharmacology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bph.15832

Reference53 articles.

1. Mitragyna speciosa, A Psychoactive Tree from Southeast Asia with Opioid Activity

2. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

3. THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: Enzymes

4. Identification of five mitragyna alkaloids in blood and tissues using liquid chromatography-quadrupole/time-of-flight mass spectrometry

5. CYP450-Mediated Metabolism of Mitragynine and Investigation of Metabolites in Human Urine

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