More evidence of the problems of using HbA1c for diagnosing diabetes? The known knowns, the known unknowns and the unknown unknowns

Author:

Church D.1,Simmons D.2

Affiliation:

1. The Department of Clinical Biochemistry Addenbrooke's Hospital Cambridge UK

2. Wolfson Diabetes & Endocrine Clinic Institute of Metabolic Science Addenbrooke's Hospital Cambridge UK

Publisher

Wiley

Reference27 articles.

1. WHO.Use of glycated haemoglobin (HbA1C) in the diagnosis of diabetes mellitus: abbreviated report of a WHO consultation. Jan 14 2011.http://www.who.int/cardiovascular_diseases/report-hba1c_2011_edited.pdf(accessed Dec 7 2013).

2. Expert Position Statement. Use of HbA1c in the diagnosis of diabetes mellitus in the UK. The implementation of World Health Organisation;John WG on behalf of the UK Department of Health Advisory Committee on Diabetes;Diabet Med,2012

3. UKPDS) Group. Intensive blood‐glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes. (UKPDS 33);UK Prospective Diabetes Study;Lancet,1998

4. Intra-individual variation of glucose, specific insulin and proinsulin concentrations measured by two oral glucose tolerance tests in a general Caucasian population: the Hoorn Study

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