Clinical, polysomnographic and genome-wide association analyses of narcolepsy with cataplexy: a European Narcolepsy Network study

Author:

Luca Gianina1,Haba-Rubio José2,Dauvilliers Yves34,Lammers Gert-Jan5,Overeem Sebastiaan6,Donjacour Claire E.5,Mayer Geert7,Javidi Sirous7,Iranzo Alex8,Santamaria Joan8,Peraita-Adrados Rosa9,Hor Hyun1,Kutalik Zoltan1011,Plazzi Giuseppe12,Poli Francesca12,Pizza Fabio12,Arnulf Isabelle13,Lecendreux Michel14,Bassetti Claudio15,Mathis Johannes15,Heinzer Raphael2,Jennum Poul16,Knudsen Stine16,Geisler Peter17,Wierzbicka Aleksandra18,Feketeova Eva19,Pfister Corinne1,Khatami Ramin20,Baumann Christian21,Tafti Mehdi12,

Affiliation:

1. Center for Integrative Genomics (CIG); University of Lausanne; Lausanne Switzerland

2. Center for Investigation and Research in Sleep (CIRS); Centre Hospitalier Universitaire Vaudois (CHUV); Lausanne Switzerland

3. INSERM-1061; Montpellier France

4. Department of Neurology; National Reference Network for Orphan Diseases (Narcolepsy and Idiopathic Hypersomnia); Gui-de-Chauliac Hospital; Montpellier France

5. Department of Neurology and Clinical Neurophysiology; Leiden University Medical Centre; Leiden the Netherlands

6. Sleep Medicine Center ‘Kempenhaeghe’; Heeze the Netherlands

7. Hephata-Clinic for Neurology; Schwalmstadt-Treysa Germany

8. Neurology Service; Hospital Clinic; Barcelona Spain

9. Sleep and Epilepsy Unit - Clinical Neurophysiology Department; Gregorio Marañón University Hospital; Madrid Spain

10. Department of Medical Genetics; University of Lausanne; Lausanne Switzerland

11. Swiss Institute of Bioinformatics; Lausanne Switzerland

12. Department of Neurological Sciences; University of Bologna/IRCCS; Istituto delle Scienze Neurologiche di; Bologna Italy

13. National Reference Network for Orphan Diseases (Narcolepsy and Idiopathic Hypersomnia); Sleep Disorders Unit; Pitié-Salpêtrière Hospital; Paris France

14. Pediatric Sleep Center; National Reference Network for Orphan Diseases (Narcolepsy and Idiopathic Hypersomnia); Robert-Debré Hospital; Paris France

15. Department of Neurology; Inselspital, Bern University Hospital and University of Bern; Bern Switzerland

16. Department of Clinical Neurophysiology; University of Copenhagen; Glostrup Denmark

17. Department of Psychiatry and Psychotherapy; Sleep Disorders and Research Center; University Hospital Regensburg; Regensburg Germany

18. Third Department of Psychiatry; Institute of Psychiatry and Neurology; Warsaw Poland

19. Department of Neurology; Faculty of Medicine; Safarikiensis University and Louis Pasteur Faculty Hospital Kosice; Kosice Slovakia

20. Sleep Medicine; Barmelweid Clinic; Barmelweid Switzerland

21. Department of Neurology; University Hospital Zurich; Zurich Switzerland

Funder

EU-NN

UCB-Pharma SA

Publisher

Wiley

Subject

Behavioral Neuroscience,Cognitive Neuroscience,General Medicine

Reference53 articles.

1. Value of the multiple sleep latency test (MSLT) for the diagnosis of narcolepsy;Aldrich;Sleep,1997

2. Short REM latency as screening tool for narcolepsy;Andlauer;Sleep,2012

3. Validation of a cataplexy questionnaire in 983 sleep-disorders patients;Anic-Labat;Sleep,1999

4. Elevated anti-streptococcal antibodies in patients with recent narcolepsy onset;Aran;Sleep,2009

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