1. Weatherall Institute of Molecular Medicine, Oxford University, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UK.
2. Neurosciences Research Group, School of Biological Sciences, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK.
3. Institute of Science and Technology in Medicine, Keele University, Staffordshire ST5 5BG, UK.