Single oral doses of netazepide (YF476), a gastrin receptor antagonist, cause dose-dependent, sustained increases in gastric pH compared with placebo and ranitidine in healthy subjects

Author:

Boyce M.1,David O.1,Darwin K.1,Mitchell T.1,Johnston A.1,Warrington S.1

Affiliation:

1. Hammersmith Medicines Research; Central Middlesex Hospital; London; UK

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Reference43 articles.

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2. Interactions of COOH-terminal fragments of cholecystokinin with receptors on dispersed acini from guinea-pig pancreas;Jensen;J Biol Chem,1982

3. Distinct cholecystokinin receptors in brain and pancreas;Innis;Proc Natl Acad Sci,1980

4. Cholecystokinin receptors;Wank;Am J Physiol,1995

5. The gastrins: their production and biological activities;Dockray;Ann Rev Physiol,2001

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