Type 2 diabetes mellitus promotes the proliferation, metastasis, and suppresses the apoptosis in oral squamous cell carcinoma

Author:

Hu Xin123,Wu Jin123,Xiong Haofeng1234,Zeng Liujun123,Wang Zijia123ORCID,Wang Can123,Huang Danni123,Zhang Tianyi123,Peng Ying123,Chen Weijun123ORCID,Xia Kun4,Su Tong123ORCID

Affiliation:

1. Department of Oral and Maxillofacial Surgery Center of Stomatology Xiangya hospital of Central South University Changsha Hunan China

2. Research Center of Oral and Maxillofacial Tumor Xiangya hospital of Central South University Changsha Hunan China

3. Institute of Oral Cancer and Precancerous Lesions Central South University Changsha Hunan China

4. Center for Medical Genetics & Hunan Key Laboratory of Medical Genetics School of Life Sciences Central South University Changsha Hunan China

Publisher

Wiley

Subject

Periodontics,Cancer Research,Otorhinolaryngology,Oral Surgery,Pathology and Forensic Medicine

Reference28 articles.

1. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries;Sung H;CA: A Cancer J Clin,2021

2. Interplay between cancer cells and M2 macrophages is necessary for miR‐550a‐3‐5p down‐regulation‐mediated HPV‐positive OSCC progression;Cao M‐X;J Exp Clin Cancer Res,2020

3. Clinicopathological and prognostic characteristics of oral squamous cell carcinomas arising in patients with oral lichen planus: A systematic review and a comprehensive meta‐analysis;González‐Moles M;Oral Oncol,2020

4. Type 2 diabetes mellitus and risk of oral cancer and precancerous lesions: a meta‐analysis of observational studies;Gong Y;Oral Oncol,2015

5. Metformin reduces the increased risk of oral squamous cell carcinoma recurrence in patients with type 2 diabetes mellitus: A cohort study with propensity score analyses;Hu X;Surg Oncol,2020

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