Randomised clinical trial: palliative long-term abdominal drains vs large-volume paracentesis in refractory ascites due to cirrhosis

Author:

Macken Lucia1,Bremner Stephen1,Gage Heather2,Touray Morro2,Williams Peter2,Crook David1,Mason Louise1,Lambert Debbie1,Evans Catherine J.13,Cooper Max1,Timeyin Jean1,Steer Shani1,Austin Mark1,Parnell Nick1,Thomson Sam J.4,Sheridan David5,Wright Mark6,Isaacs Peter7,Hashim Ahmed1,Verma Sumita1ORCID

Affiliation:

1. Brighton UK

2. Guildford UK

3. London UK

4. Worthing UK

5. Plymouth UK

6. Southampton UK

7. Blackpool UK

Funder

National Institute for Health Research, Research for Patient Benefit

Kent Surrey and Sussex Deanery

Dunhill Medical Trust

NIHR Biomedical Research Centre for Mental Health at South London

Maudsley NHS Foundation Trust

King's College London

NIHR Evaluation, Trials and Studies Coordinating Centre

Publisher

Wiley

Subject

Pharmacology (medical),Gastroenterology,Hepatology

Reference46 articles.

1. Public Health England The 2nd Atlas of variation in risk factors and healthcare for liver disease in England https://fingertips.phe.org.uk/profile/atlas-of-variation

2. The rate of decompensation and clinical progression of disease in people with cirrhosis: a cohort study;Fleming;Aliment Pharmacol Ther,2010

3. EASL Practice Guidelines for the management of patients with decompensated cirrhosis. European Association for the Study of the Liver;J Hepatol,2018

4. External validation of a prognostic model for predicting survival of cirrhotic patients with refractory ascites;Guardiola;Am J Gastroenterol,2002

5. The utility of the model for end-stage liver disease score - a reliable guide for liver transplant candidacy and for select patients, simultaneous hospice referral;Medici;Liver Transpl,2008

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