CD4+ T‐cell lymphopenia in frequent platelet donors who have ceased platelet donation for at least 1 year

Author:

Rahmani Mahboubeh1,Fortin Brooke M.2,Berliner Nancy2,Issa Nicolas3,Neuberg Donna4,Kaufman Richard M.5,Gansner John M.2

Affiliation:

1. Division of HematopathologyDalhousie University Halifax Nova Scotia Canada

2. Hematology DivisionBrigham and Women's Hospital Boston Massachusetts

3. Division of Infectious DiseasesBrigham and Women's Hospital Boston Massachusetts

4. Department of Biostatistics and Computational BiologyDana‐Farber Cancer Institute Boston Massachusetts

5. Department of PathologyBrigham and Women's Hospital Boston Massachusetts

Funder

K12 award from the National Heart, Lung, and Blood Institute of the National Institutes of Health

Dana-Farber/Harvard Cancer Center Comprehensive Cancer Center grant from the National Cancer Institute

Publisher

Wiley

Subject

Hematology,Immunology,Immunology and Allergy

Reference11 articles.

1. Food and Drug Administration. Guidance for industry and FDA review staff: collection of platelets by automated methods. US Department of Health and Human Services 2007: 1 30.

2. ParkmanP.Revised guideline for the collection of platelets pheresis. Bethesda (MD): Food and Drug Administration (Division of Blood and Blood Products Center for Biologics Evaluation and Research);1988Oct.

3. Apheresis donor safety - changes in humoral and cellular immunity

4. The safety of weekly plateletpheresis: effect on the donors' lymphocyte population

5. Lymphocytopenia in donors undergoing regular platelet apheresis with cell separators

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