Acid Sphingomyelinase Down-regulation Alleviates Vascular Endothelial Insulin Resistance in Diabetic Rats

Author:

Li Xin1,Jin Shi-Jie2,Su Jie1,Li Xiao-Xue3,Xu Ming1

Affiliation:

1. Department of Clinical Pharmacy; School of Preclinical Medicine and Clinical Pharmacy; China Pharmaceutical University; Nanjing China

2. School of Pharmacy; Zhejiang Chinese Medical University; Hangzhou China

3. Department of Pathology; Medical School of Southeast University; Nanjing China

Funder

National Natural Science Foundation of China

National Natural Science Foundation of Jiangsu

Publisher

Wiley

Subject

Pharmacology,Toxicology,General Medicine

Reference42 articles.

1. Metabolic syndrome and insulin resistance: underlying causes and modification by exercise training;Roberts;Compr Physiol,2013

2. Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes;Caballero;Diabetes,1999

3. Is insulin resistance atherogenic? Possible mechanisms;Defronzo;Atheroscler Suppl,2006

4. The unexpected role of acid sphingomyelinase in cell death and the pathophysiology of common diseases;Smith;FASEB J,2008

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