Alantolactone is a natural product that potently inhibits YAP1/TAZ through promotion of reactive oxygen species accumulation-Reference-Cited by-同舟云学术

Alantolactone is a natural product that potently inhibits YAP1/TAZ through promotion of reactive oxygen species accumulation

Published:2021-08-06 Issue:10 Volume:112 Page:4303-4316
ISSN:1347-9032
Container-title:Cancer Science
language:en
Short-container-title:Cancer Sci

Author:

Nakatani Keisuke¹²³,Maehama Tomohiko¹^ORCID,Nishio Miki¹,Otani Junji¹,Yamaguchi Keiko¹,Fukumoto Miki¹,Hikasa Hiroki²⁴,Hagiwara Shinji³,Nishina Hiroshi⁵,Mak Tak Wah⁶⁷⁸,Honma Teruki⁹,Kondoh Yasumitsu¹⁰,Osada Hiroyuki¹⁰,Yoshida Minoru¹¹¹²,Suzuki Akira¹²^ORCID

Affiliation:

1. Division of Molecular and Cellular Biology Kobe University Graduate School of Medicine Kobe Japan

2. Medical Institute of Bioregulation Kyushu University Fukuoka Japan

3. Bio Science and Engineering Laboratory Research and Development Management HeadquartersFujiFilm Corporation Kanagawa Japan

4. Department of Biochemistry School of Medicine University of Occupational and Environmental Health Fukuoka Japan

5. Medical Research Institute Department of Developmental and Regenerative Biology Tokyo Medical and Dental University Tokyo Japan

6. Princess Margaret Cancer Centre University Health Network Toronto Ontario Canada

7. Departments of Immunology and Medical Biophysics University of Toronto Toronto ON Canada

8. Department of Pathology LKS Faculty of Medicine The University of Hong Kong Hong Kong SAR

9. RIKEN Center for Biosystems Dynamics Research Yokohama Japan

10. Chemical Biology Research Group RIKEN Center for Sustainable Resource Science Wako Japan

11. Chemical Genomics Research Group RIKEN Center for Sustainable Resource Science Wako Japan

12. Department of Biotechnology Graduate School of Agricultural and Life Sciences The University of Tokyo Tokyo Japan

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/cas.15079

Reference66 articles.

1. Hippo vs. Crab: tissue-specific functions of the mammalian Hippo pathway

2. YAP1 is a potent driver of the onset and progression of oral squamous cell carcinoma

3. Endogenous YAP1 activation drives immediate onset of cervical carcinoma in situ in mice

4. The role of Hippo‐YAP signaling in squamous cell carcinomas

5. Dysregulated YAP1/TAZ and TGF-β signaling mediate hepatocarcinogenesis in Mob1a/1b-deficient mice

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