Affiliation:
1. Department of Rehabilitation Medicine Xuzhou Rehabilitation Hospital Affiliated to Xuzhou Medical University Xuzhou China
2. Department of Rehabilitation Medicine, Xuzhou Central Hospital The Xuzhou Clinical College of Xuzhou Medical University Xuzhou China
Abstract
ABSTRACTObjectiveConstruction nomogram was to effectively predict long‐term prognosis in patients with non‐small cell lung cancer (NSCLC).Materials and MethodsThe nomogram is developed by a retrospective study of 347 patients with NSCLC who underwent cardiopulmonary exercise testing (CPET) before surgery from May 2019 to February 2022. Cross‐validation divided the data into a training cohort and validation cohort. The discrimination and accuracy ability of the nomogram were proofed by concordance index (C‐index), calibration curve, receiver operating characteristic (ROC) curve, the area under the curve (AUC), and time‐dependent ROC in validation cohort.ResultsAge, intraoperative blood loss, VO2 peak, and VE/VCO2 slope were included in the model of nomogram. The model demonstrated good discrimination and accuracy with C‐index of 0.770 (95% CI: 0.712–0.822). AUC of 6 (AUC: 0.789, 95% CI: 0.726–0.851) and 12 months (AUC: 0.787, 95% CI: 0.724–0.850) were shown in ROC. Time‐independent ROC maintains a good effect within 12 months.ConclusionWe developed a nomogram based on CPET. This model has a good ability of discrimination and accuracy. It could help clinicians to make treatment decision in clinical decision.