Lipoarabinomannan mannose caps do not affect mycobacterial virulence or the induction of protective immunity in experimental animal models of infection and have minimal impact onin vitroinflammatory responses

Author:

Afonso-Barroso António1,Clark Simon O.2,Williams Ann2,Rosa Gustavo T.1,Nóbrega Cláudia3,Silva-Gomes Sandro1,Vale-Costa Sílvia1,Ummels Roy4,Stoker Neil5,Movahedzadeh Farahnaz,van der Ley Peter6,Sloots Arjen6,Cot Marlène,Appelmelk Ben J.4,Puzo Germain,Nigou Jérôme,Geurtsen Jeroen4,Appelberg Rui1

Affiliation:

1. Institute for Molecular and Cell Biology (IBMC); University of Porto; Porto; Portugal

2. Microbiology Services-Porton Down; Health Protection Agency; Salisbury, Wiltshire; SP4 0JG; UK

3. Life and Health Sciences Research Institute (ICVS); School of Health Sciences; University of Minho; ICVS/3B's-PT Government Associate Laboratory; Braga/Guimarães; Portugal

4. Department of Medical Microbiology and Infection Control; VU University Medical Center; 1081 BT; Amsterdam; the Netherlands

5. Department of Pathology and Infectious Diseases; Royal Veterinary College; London; UK

6. RIVM-National Institute of Public Health and the Environment; Bilthoven; the Netherlands

Publisher

Hindawi Limited

Subject

Virology,Immunology,Microbiology

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