Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma-Reference-Cited by-同舟云学术

Dual inhibition of enhancer of zeste homolog 1/2 overactivates WNT signaling to deplete cancer stem cells in multiple myeloma

Published:2018-11-16 Issue:1 Volume:110 Page:194-208
ISSN:1347-9032
Container-title:Cancer Science
language:en
Short-container-title:Cancer Sci

Author:

Nakagawa Makoto¹²,Fujita Shuhei¹,Katsumoto Takuo¹,Yamagata Kazutsune¹,Ogawara Yoko¹,Hattori Ayuna¹,Kagiyama Yuki¹³,Honma Daisuke⁴,Araki Kazushi⁴,Inoue Tatsuya⁵,Kato Ayako⁵,Inaki Koichiro⁵,Wada Chisa⁵,Ono Yoshimasa⁵,Yamamoto Masahide⁶,Miura Osamu⁶,Nakashima Yasuharu²,Kitabayashi Issay¹^ORCID

Affiliation:

1. Division of Hematological Malignancy; National Cancer Center Research Institute; Tokyo Japan

2. Department of Orthopaedic Surgery; Graduate School of Medical Sciences; Kyushu University; Fukuoka Japan

3. Laboratory of Oncology; School of Life Sciences; Tokyo University of Pharmacy and Life Sciences; Tokyo Japan

4. Oncology Laboratories; Daiichi Sankyo Co., Ltd; Tokyo Japan

5. Functional Genomics and Proteomics Research Group; Discovery Science and Technology Department; Daiichi Sankyo RD Novare Co., Ltd; Tokyo Japan

6. Department of Hematology; Graduate School of Medical and Dental Sciences; Tokyo Medical and Dental University; Tokyo Japan

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

National Cancer Center Research and Development Fund

Publisher

Wiley

Subject

Cancer Research,Oncology,General Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1111/cas.13840/fullpdf

Reference51 articles.

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3. Multiple drug resistance in cancer revisited: the cancer stem cell hypothesis;Donnenberg;J Clin Pharmacol,2005

4. Cytokinetically quiescent (G0/G1) human multiple myeloma cells are susceptible to simultaneous inhibition of Chk1 and MEK1/2;Pei;Blood,2011

5. The ABC transporter Bcrp1/ABCG2 is expressed in a wide variety of stem cells and is a molecular determinant of the side-population phenotype;Zhou;Nat Med,2001

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