Adult brain tumour research in 2024: Status, challenges and recommendations-Reference-Cited by-同舟云学术

Adult brain tumour research in 2024: Status, challenges and recommendations

Published:2024-04 Issue:2 Volume:50 Page:
ISSN:0305-1846
Container-title:Neuropathology and Applied Neurobiology
language:en
Short-container-title:Neuropathology Appl Neurobio

Author:

Purshouse Karin¹,Bulbeck Helen J.²,Rooney Alasdair G.³,Noble Karen E.⁴,Carruthers Ross D.⁵,Thompson Gerard³⁶,Hamerlik Petra⁷,Yap Christina⁸,Kurian Kathreena M.⁹,Jefferies Sarah J.¹⁰,Lopez Juanita S.¹¹,Jenkinson Michael D.¹²,Hanemann C. Oliver¹³,Stead Lucy F.¹⁴^ORCID

Affiliation:

1. Institute of Genetics and Cancer The University of Edinburgh Edinburgh UK

2. Brainstrust Cowes UK

3. Centre for Clinical Brain Sciences The University of Edinburgh Edinburgh UK

4. Brain Tumour Research Milton Keynes UK

5. Beatson West of Scotland Cancer Centre Glasgow UK

6. Department of Clinical Neurosciences NHS Lothian Edinburgh UK

7. Division of Cancer Sciences University of Manchester Manchester UK

8. Clinical Trials and Statistics Unit Sutton UK

9. Bristol Brain Tumour Research Centre, Bristol Medical School University of Bristol Bristol UK

10. Oncology Department Addenbrooke's Hospital Cambridge UK

11. Royal Marsden NHS Foundation Trust and the Institute of Cancer Research Sutton UK

12. University of Liverpool & Walton Centre Liverpool UK

13. Peninsula Medical School University of Plymouth Plymouth UK

14. Leeds Institute of Medical Research University of Leeds Leeds UK

Abstract

AbstractIn 2015, a groundswell of brain tumour patient, carer and charity activism compelled the UK Minister for Life Sciences to form a brain tumour research task and finish group. This resulted, in 2018, with the UK government pledging £20m of funding, to be paralleled with £25m from Cancer Research UK, specifically for neuro‐oncology research over the subsequent 5 years. Herein, we review if and how the adult brain tumour research landscape in the United Kingdom has changed over that time and what challenges and bottlenecks remain. We have identified seven universal brain tumour research priorities and three cross‐cutting themes, which span the research spectrum from bench to bedside and back again. We discuss the status, challenges and recommendations for each one, specific to the United Kingdom.

Funder

UK Research and Innovation

Cancer Research UK

Brain Tumour Charity

Sir John Fisher Foundation

Royal College of Surgeons of England

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/nan.12979

Reference75 articles.

1. Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. GBMPurity: A Machine Learning Tool for Estimating Glioblastoma Tumour Purity from Bulk RNA-seq Data;2024-07-16