Risk assessment of medically assisted reproduction and advanced maternal ages in the development of Prader-Willi syndrome due to UPD(15)mat

Author:

Matsubara K.12,Murakami N.2,Fukami M.1,Kagami M.1,Nagai T.2,Ogata T.13

Affiliation:

1. Department of Molecular Endocrinology; National Research Institute for Child Health and Development; Tokyo Japan

2. Department of Pediatrics; Dokkyo Medical University Koshigaya Hospital; Koshigaya Japan

3. Department of Pediatrics; Hamamatsu University School of Medicine; Hamamatsu Japan

Funder

Scientific Research

Young Scientists

Japan Agency for Medical Research and Development (AMED)

National Center for Child Health and Development

Publisher

Wiley

Subject

Genetics (clinical),Genetics

Reference20 articles.

1. Prader-Willi syndrome;Cassidy;Genet Med,2012

2. Mechanisms leading to uniparental disomy and their clinical consequences;Robinson;Bioessays,2000

3. American College of Medical Genetics statement of diagnostic testing for uniparental disomy;Shaffer;Genet Med,2001

4. Meiosis and maternal aging: insights from aneuploidy oocytes and trisomy births;Herbert;Cold Spring Harb Perspect Biol,2015

5. Nondisjunction of chromosome 15: origin and recombination;Robinson;Am J Hum Genet,1993

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