Effect of Lumenato a Tomato derived oral supplement on improving skin barrier strength

Author:

Tarshish Elizabeth1,Hermoni Karin2,Muizzuddin Neelam3

Affiliation:

1. Lycored Ltd Beer Sheva Israel

2. Lycored CORP Secaucus New Jersey USA

3. Skin Clinical Research Consultants LLC Bethpage New York USA

Abstract

AbstractIntroductionImprovement of skin barrier strength could lead to healthy and youthful appearance. “Beauty inside‐out” approach using nutraceuticals such as tomato derived carotenoids to support skin barrier strength could be of benefit to the ageing population.MethodA panel of 60 female subjects were provided with the Lumenato capsules (containing carotenoids) or placebo capsules as nutritional supplements for 3 months. Skin health and barrier function were observed using evaporimeter which measures trans epidermal water loss (TEWL). Barrier strength was determined by study of the number of strippings required to disrupt skin barrier and barrier repair was observed in terms of TEWL a few hours after barrier disruption. Cutometer was used to observe skin firmness and elasticity. Measurements were obtained before treatment and after 4 and 12 weeks of use.ResultsResults indicated a statistically significant improvement (p < 0.05) in skin barrier strength; a higher number of strippings were required to disrupt skin barrier after 12 weeks of supplement use. There was also a significant improvement in skin firmness and elasticity as observed with a cutometer.ConclusionBased on the confines and conditions of this study, oral supplementation with Lumenato resulted in significant improvement in skin barrier as well as skin firmness and elasticity.

Publisher

Wiley

Subject

Dermatology

Reference62 articles.

1. The clinical relevance of maintaining the functional integrity of the stratum corneum in both healthy and disease‐affected skin;Del Rosso JQ;J Clin Aesthet Dermatol,2011

2. Barrier function regulates epidermal lipid and DNA synthesis

3. Water Distribution and Related Morphology in Human Stratum Corneum at Different Hydration Levels

4. The Human Skin Barrier Is Organized as Stacked Bilayers of Fully Extended Ceramides with Cholesterol Molecules Associated with the Ceramide Sphingoid Moiety

5. Understanding the epidermal barrier in healthy and compromised skin: clinically relevant information for the dermatology practitioner proceedings of an expert panel roundtable meeting;Del Rosso J;Supp J Clin Aesthetic Derm,2016

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3