Progress and recognition of idiopathic intracranial hypertension: A narrative review

Author:

Zhou Chenxia12,Zhou Yifan3,Liu Lu124,Jiang Huimin3,Wei Huimin5,Zhou Chen23,Ji Xunming236ORCID

Affiliation:

1. Department of Neurology Xuanwu Hospital, Capital Medical University Beijing China

2. Neurology and Intracranial Hypertension and Cerebral Venous Disease Center National Health Commission of China, Xuanwu Hospital, Capital Medical University Beijing China

3. Laboratory of Brain Disorders, Ministry of Science and Technology, Collaborative Innovation Center for Brain Disorders Beijing Institute of Brain Disorders, Beijing Advanced Innovation Center for Big Data‐based Precision Medicine, Capital Medical University Beijing China

4. Zhongguancun Xirui Institute of Precision Medicine for Heart and Brain Tumors Beijing China

5. Beijing Advanced Innovation Center for Big Data‐Based Precision Medicine School of Biological Science and Medical Engineering, Beihang University Beijing China

6. Department of Neurosurgery Xuanwu Hospital, Capital Medical University Beijing China

Abstract

AbstractBackgroundIdiopathic intracranial hypertension (IIH) mainly affects obese young women, causing elevated intracranial pressure, headaches, and papilledema, risking vision loss and severe headaches. Despite weight loss as the primary treatment, the underlying mechanisms remain unclear. Recent research explores novel therapeutic targets.AimsThis review aimed to provide a comprehensive understanding of IIH's pathophysiology and clinical features to inform pathogenesis and improve treatment strategies.MethodsRecent publications on IIH were searched and summarized using PubMed, Web of Science, and MEDLINE.ResultsThe review highlights potential pathomechanisms and therapeutic advances in IIH.ConclusionIIH incidence is rising, with growing evidence linking it to metabolic and hormonal disturbances. Early diagnosis and treatment remain challenging.

Funder

National Natural Science Foundation of China

Publisher

Wiley

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