Calorie restriction in humans inhibits the PI 3 K / AKT pathway and induces a younger transcription profile-Reference-Cited by-同舟云学术

Calorie restriction in humans inhibits the PI 3 K / AKT pathway and induces a younger transcription profile

Published:2013-06-05 Issue:4 Volume:12 Page:645-651
ISSN:1474-9718
Container-title:Aging Cell
language:en
Short-container-title:Aging Cell

Author:

Mercken Evi M.¹,Crosby Seth D.²,Lamming Dudley W.³⁴⁵⁶⁷,JeBailey Lellean⁸,Krzysik‐Walker Susan⁹,Villareal Dennis T.¹⁰,Capri Miriam¹¹¹²,Franceschi Claudio¹¹¹²,Zhang Yongqing¹³,Becker Kevin¹³,Sabatini David M.³⁴⁵⁶⁷,Cabo Rafael¹,Fontana Luigi¹⁰¹⁴¹⁵

Affiliation:

1. Laboratory of Experimental Gerontology National Institute on Aging National Institutes of Health Baltimore MD 21224USA

2. Department of Genetics Washington University School of Medicine St. Louis MO 63108USA

3. Whitehead Institute for Biomedical Research Cambridge MA 02142USA

4. Department of Biology Massachusetts Institute of Technology (MIT) Cambridge MA 02139USA

5. Howard Hughes Medical Institute MIT Cambridge MA 02139USA

6. Broad Institute of Harvard and MIT Seven Cambridge Center Cambridge MA 02142USA

7. The David H. Koch Institute for Integrative Cancer Research at MIT Cambridge MA 02139USA

8. GeneGo Inc. St. Joseph MI 49085USA

9. Laboratory of Clinical Investigation National Institute on Aging National Institutes of Health Baltimore MD 21224USA

10. Division of Geriatrics and Nutritional Science Washington University School of Medicine St. Louis MO 63108USA

11. CIG ‐ Interdepartmental Centre “Galvani” University of Bologna‐ ALMA MATER STUDIORUM Bologna 40126Italy

12. Department of Experimental Diagnostic and Specialty Medicine University of Bologna‐ ALMA MATER STUDIORUM Bologna 40126Italy

13. Gene Expression and Genomics Unit National Institute on Aging National Institutes of Health Baltimore MD 21224 USA

14. Department of Medicine Salerno University Medical School Salerno 84081 Italy

15. CEINGE Biotecnologie Avanzate Napoli 80145 Italy

Funder

AFAR

National Institutes of Health

NIH Roadmap for Medical Research

National Center for Research Resources

National Institute of Diabetes And Digestive And Kidney Diseases

National Institute on Aging-Intramural Research Program

Longer Life Foundation

Bakewell Foundation

Calorie Restriction Society and the Scott and Annie Appleby Charitable Trust

NCI Cancer Center

Publisher

Wiley

Subject

Cell Biology,Aging

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/acel.12088

Reference26 articles.

1. Metabolic reprogramming in dietary restriction;Anderson RM;Interdiscip Top Gerontol.,2007

2. Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle

3. Stress-Dependent Regulation of FOXO Transcription Factors by the SIRT1 Deacetylase

4. An in vitro model of caloric restriction

5. Long-term effects of calorie restriction on serum sex-hormone concentrations in men

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